Blacktip reef sharks are very important members of the ecosystems that they inhabit, primarily because they are often the apex predator in the food chain. They are currently listed as near threatened on the IUCN red list, and their current population trend is defined as decreasing. While their populations are not fragmented from one another, they are mainly declining because blacktip reef sharks often end up as bycatch in many inshore fisheries.
Blacktip reef sharks are still widespread and their numbers are higher than many other shark species. However, due to overfishing and the slow reproductive tendencies of this species, they are considered to be near threatened.